Method Development of Analysis

Method Development of Analysis (Validation and verification of analytical method) Food Packaging

 No.

 Method of analysis

 LOD

LOQ 

Techniques 

 1.

Enameled / aluminium / stainless steel cookware, paper, wood Zleaching of heavy metals below)
- Lead
- Cadmium

 -




0.02 ppm1,0.1 ppm2, 0.1 ppm3
0.005 ppm1, 0.01 ppm2, 0.01 ppm3

Graphite -furnance1
Flame AAS2
ICP-OES3

 2.

 Overall migration by food simulants :
- 10% ethanol
- 3% acetic acid
- 20% ethanol
- 50% ethanol
- Vegetable oil
- Tenax

0.5 mg/dm2
0.5 mg/dm2
0.5 mg/dm2
0.5 mg/dm2
0.2 mg/dm2
0.4 mg/dm2

1.0 mg/dm2
1.0 mg/dm2
1.0 mg/dm2
1.0 mg/dm2
0.5 mg/dm2
1.5 mg/dm2

Gravimetric method

3.

Extractable by Xylene for plastic packaging containing milk and milk product

 1.5 ppm

 5 ppm

Gravimetric method

4.

Extractable by hexane for plastic packaging containing milk and milk product

 1.5 ppm

 5 ppm

Gravimetric method

 5.

Lead in plastic packaging

 0.04 mg/kg

 0.2 mg/kg

AAS

 6.

Cadmium in plastic packaging

 0.01 mg/kg

 0.05 mg/kg

AAS

 7.

ATBC, DINCH, Sebacate and Phthalates in food
- Di-2-ethylhexyl phthalate (DEHP)
- Di-isononyl phthalate (DINP)
- Di-iso-decyl phthalate (DIDP)
- Dibutyl phthalate (DBP)
- Benzylbutyl phthalate (BBP)



0.2 mg/kg
3.0 mg/kg
3.0 mg/kg
0.1 mg/kg
0.1 mg/kg



0.6 mg/kg
9.0 mg/kg
9.0 mg/kg
0.3 mg/kg
0.3 mg/kg

GC-MS with PTV injection

 8.

Nitrosamine

 3 μg/kg

 8 μg/kg

LC/MS/MS

 9.

Melamine      
 10. 3 ring to 6 ring NOGE

 0.3 μg/ml

 1 μg/ml

HPLC
 11. Corrosion rate of canned food

 -

  Tafel plot
technique
 12. Resistance of lacquered canned food

 -

  A.C. impedance